Great for families, patients, academics, visitors and friends, given its spot in the, ahem, heart of Longwood Medical.

Free breakfast spread with both healthy and indulgent options, plus an evening social several nights a week.

A perf jumping-off point in the thick of Worcester, within easy reach of the Mass Pike (pro tip: locals pronounce it Woost-ah).

Coolly sophisticated design that's as sleek as it is comfortable.

Easy Boston connection, right by the Mass Pike and commuter rail.

Grand, marbled & gilded lobby impresses, and the luxe vibe extends to elegant but contemporary guest rooms.

History buffs will dig the gastropub, with live music & 3 dining areas – one formerly a ‘men’s only’ bar & one a Revolutionary War storeroom.

Pleasant stay 4 miles from Boston, with onsite dining, fitness room and li’l mini-mart for the inevitable forgotten something or other. Also: snacks.

Nestled in the heart of the historic Bridge Street Neck District, you’re less than a mile from Salem Common and the must-visit Salem Witch Museum.

Modern style is simple with just a touch of posh.

Easy access to Logan International and downtown Boston (win-win).

Just 1 mile from the Boston Convention & Exposition Center and right across the street from the T station for easy access to local sights.

Killer North Shore location for work or play (or a bit of both).

Feel like sneaking in a li'l sightseeing? You're a mere 12 miles to Boston Common & all its historic to-dos.

Well-equipped gym will please fitness fanatics, as will the gear & apparel rental program that lets ‘em pack light.

Onsite breakfast restaurant Against the Grain has an American breakfast right at your doorstep.

Free breakfast to keep hanger at bay.

A quick 5-min zip to/from the airport to make making your flight less hyperventilate-y.

Exquisite and updated rooms feature bath and body products by Diptyque and an iPad on every table.

Dating from the 19th century, the property was home to one of the town’s founding families – and is now family owned, giving it a true homey feel.

Invigoratingly modern with accents that reference Boston's long history.

Suite-style digs, so there’s less stepping over suitcases. Plus full kitchen for meal-making or sammie-assembling should you feel so inclined.

Innovation District address puts you within strolling distance of the World Trade Center, Institute of Contemporary Art & Financial District.

Bring your furry friends along for the ride. This place is pet friendly.

Built by a local icon, these digs boast past lives as a rare book store, tavern & host to greats like George Washington.

Plush old-school vibe is brimming with classic charm.

Gorgeous newly restored hotel steps from the public garden

Sweet boutique find perched atop North Station (with a terrace!), a 1-min jaunt to TD Garden.

Elegant sophistication in the heart of Beacon Hill. Steps from the Charles River, you're surrounded by bars and restaurants.

Just north of the city and not far from the airport.

Rooms score big, with contemporary furniture earning style points and pillow-top beds snagging comfort points.